trimipramine hydrogen maleate
Trimipramine Maleate Salt
CAS: 521-78-8
Molecular Formula: C24H30N2O4
trimipramine hydrogen maleate - Names and Identifiers
trimipramine hydrogen maleate - Physico-chemical Properties
| Molecular Formula | C24H30N2O4 |
| Molar Mass | 410.51 |
| Melting Point | 141-143°C |
| Flash Point | 11°C |
| Solubility | chloroform: soluble50 mg/ml, clear, colorless to faintly yellow |
| Appearance | powder |
| Color | white |
| Storage Condition | 2-8°C |
| Use | This product is for scientific research only and shall not be used for other purposes. |
| In vitro study | Trimipramine displays much higher affinity for 5-HT 2 than for 5-HT 1C receptors. |
| In vivo study | The chronic administration of Trimipramine (5 mg/kg/day), as delivered by the osmotic minipump in 14 days produce significant increases in the regional concentration of 5-HT. The increases are highest in the frontal cortex and the hippocampus, followed by the olfactory tubercles and the hypothalamus. The Trimipramine treatment also produces marked increases in brain 5-HIAA concentrations ranging from 63% in the hippocampus to 25% in the nucleus accumbens with intermediate values for the hypothalamus, olfactory tubercles, frontal cortex and nucleus accumbens. Trimipramine treatment produces significant increases in DA concentrations in the nucleus accumbens, striaturn, and olfactory tubercles reaching 43, 21 and 11% respectively. Chronic administration of Trimipramine produces a marked reduction in the number of frontal cortex 5-HT 2 and striatal DA D 2 receptors. The chronic administration of Trimipramine produces an increase in the brain regional level of monoamines and metabolites indicating a greater synthesis rate for DA and 5-HT coinciding with an adaptive down regulation of 5-HT 2 and DA D 2 receptors. |
trimipramine hydrogen maleate - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. R63 - Possible risk of harm to the unborn child R36/38 - Irritating to eyes and skin. R23/25 - Toxic by inhalation and if swallowed. R39/23/24/25 - R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R11 - Highly Flammable |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S33 - Take precautionary measures against static discharges. S24 - Avoid contact with skin. S16 - Keep away from sources of ignition. S7 - Keep container tightly closed. S36/37 - Wear suitable protective clothing and gloves. |
| UN IDs | 3249 |
| WGK Germany | 3 |
| RTECS | HN9260000 |
| HS Code | 2933996100 |
| Hazard Class | 6.1(b) |
| Packing Group | III |
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Multiple SpecificationsSpot supply
Product Name: Trimipramine Maleate Salt Visit Supplier Webpage Request for quotationCAS: 521-78-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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